{
  "resourceType" : "Observation",
  "id" : "obs-diagnostic-min",
  "meta" : {
    "profile" : ["https://nhicore.nhi.gov.tw/pas/StructureDefinition/Observation-diagnostic-twpas"]
  },
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Observation-diagnostic-twpas.html\">基因資訊-Observation Diagnostic TWPAS</a></p></div><p><b>狀態</b>：final</p><p><b>類型</b>：基因資訊<span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-nhi-supporting-info-type.html/\">NHI-補充資訊類別值集</a>#geneInfo)</span></p><p><b>code</b>：Genetic variant assessment<span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://loinc.org/\">LOINC</a>#69548-6)</span></p><p><b>病人</b>：<a href=\"Patient-pat-min.html\">Patient/pat-min</a></p><p><b>基因檢測日期</b>：2024-05-07</p><blockquote><p><b>基因檢測代碼</b>：KRAS gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\">（ <a href=\"http://loinc.org/\">LOINC-基因檢測代碼值集</a>#21702-6）</span><br/><b>基因檢測實際結果</b>：KRAS 12 mutation: Not Detected, KRAS 13 mutation: Not Detected, KRAS 61 mutation: Not Detected<br/><b>基因突變類型</b>：Not detected <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\">（ <a href=\"http://loinc.org/\">LOINC-基因突變類型值集</a>#LA11883-8）</span></p></blockquote><p><b>基因檢測機構</b>：<a href=\"Organization-org-gene-example.html\">Organization 2023LDTB0002</a></p><p><b>基因檢測分析結果</b>：基因檢測報告結果</p><p><b>基因臨床判讀結果</b>：Positive <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\">(<a href=\"http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation/\">ObservationInterpretationCodes </a>#POS)</span></p><p><b>基因檢測方法</b>：PCR <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\">(<a href=\"http://loinc.org/\">LOINC Answer List LL4048-6 </a>#LA26418-6)</span></p><p><b>基因檢測檢體類型</b>：<a href=\"Specimen-spe-min.html\">Specimen/spe-min</a></p><p><b>基因報告</b>：<a href=\"DocumentReference-doc-gene-min.html\">DocumentReference/doc-gene-min</a></p></div>"
  },
  "status" : "final",
  "category" : [{
    "coding" : [{
      "system" : "https://nhicore.nhi.gov.tw/pas/CodeSystem/nhi-supporting-info-type",
      "code" : "geneInfo"
    }]
  }],
  "code" : {
    "coding" : [{
      "system" : "http://loinc.org",
      "code" : "69548-6"
    }]
  },
  "subject" : {
    "reference" : "Patient/pat-min"
  },
  "effectiveDateTime" : "2024-05-07",
  "performer" : [{
    "reference" : "Organization/org-gene-example"
  }],
  "valueString" : "基因檢測報告結果",
  "interpretation" : [{
    "coding" : [{
      "system" : "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
      "code" : "POS"
    }]
  }],
  "method" : {
    "coding" : [{
      "system" : "http://loinc.org",
      "code" : "LA26418-6"
    }]
  },
  "specimen" : {
    "reference" : "Specimen/spe-min"
  },
  "derivedFrom" : [{
    "reference" : "DocumentReference/doc-gene-min"
  }],
  "component" : [{
    "code" : {
      "coding" : [{
        "system" : "http://loinc.org",
        "code" : "21702-6"
      }]
    },
    "valueString" : "KRAS 12 mutation: Not Detected, KRAS 13 mutation: Not Detected, KRAS 61 mutation: Not Detected",
    "interpretation" : [{
      "coding" : [{
        "system" : "http://loinc.org",
        "code" : "LA11883-8",
        "display" : "Not detected"
      }],
      "text" : "Not detected"
    }]
  }]
}